I just finished playing through a mod for Civilization 4 called Dune Wars. It is possibly the best Dune video game I've ever played, and it has inspired me to work on a Houses of Dune game. I'm thinking of running just such a game when my current HotB game ends very soon.
I think most things will be able to stay the same with a few additions and slight tweaks.
I'm of two minds right now regarding the +1 Bonus to aspects - either you get it based off of your House or your Caste. I think I'm leaning towards the idea that each Family name (including any Fremen name) is an aspect. So the Harkonnen get an aggressive aspect that also tags them for their legendary short-tempers. Thus, the +1 Aspect Bonus is based upon your Caste. Bene-Gesserit/Nobles have Cunning, Fedaykin/Saddukar/etc. have Prowess, Fremen Scouts/Smugglers/Liet Kienes and his folk have Courage, Mentats/Guilders have Wisdom, Gladiators/Deep Desert Fremen have Strength, and Imperials/Consorts have Beauty.
There won't be artifacts anymore, but there will be Technologies. Much like Artifacts Technologies will give special bonuses, many will stay the same, but others will change. Examples include, Stillsuits, Thumpers, Hunter-Killers and The Juice of Saffo. Possibly also flying vehicles...we shall see.
Devotions will also change. You will chose an ideal. The Landsraad (Duke Leto I), Shai'Hu'lud (Early Fremen/Stilgar), The Quizate (Gaius Helena Mohan/Leto II), The Ma'haud'i (Paul Atreidies/Alia), The Technocracy (The Spacing Guild/Ix/Tilaxia), Kanly (Baron Harkonnen) and last but not least The Imperium (House Corrino). Devotion to this ideal will give you bonus dice when supporting this ideal directly or possibly special Devotions that give you situation specific devotions (The Weirding Way, etc.).
And almost as importantly Dueling will be updated. Knives are important as are shields. I have an idea, an idea I was already considering for regular HotB duels - to use cards based on a duelist's Maneuvers that they can play back and forth quickly. Also, a few new man. will be modded/added to account for the use of shields, and perhaps grant each character with the Duelist Aspect a number of free Maneuvers equal to their Prowess.
Finally, Season Actions will be updated to fit the technology and situation.
What does everyone think? Any thoughts?
